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The Internet Journal of Minimally Invasive Spinal Technology ISSN: 1937-8254


Facet Nerve Denervation: Where is the evidence


Serdar Erdine MD, FIPP Department of Algology, Medical Faculty of Istanbul

Citation:  S. Erdine: Facet Nerve Denervation: Where is the evidence. The Internet Journal of Minimally Invasive Spinal Technology. 2008 Supplement I - to IJMIST Vol 1 No 2


Abstract

Radiofrequency facet denervation consists of applying Radiofrequency thermocoagulation to the median branch of the dorsal ganglion supplying the innervation of the facet joints with a rationale to alleviate pain in that region. Although very frequently used in many pain centers, studies showing the evidence are minuscule. There are two systematic reviews of RCT s on radiofrequency facet denervation which may be seriously considered.(Geurts et al 2001,Niemisto et al 2003- Cochrane review) The Cochrane review included 4 studies of facet denervation.(Gallagher 1994,Lecraire 2001,Sanders and Zuurmond 1999,van Kleef 1999). There is conflicting evidence that RF denervation is more successful then placebo for eliciting short-term or long-term improvements in pain or functional disability in mechanical chronic low back pain.(Level C) There is also limited evidence that intraarticular denervation is more effective then extra-articular denervation. (Level C) Patients subject to chronic facet pain are the candidates for facet denervation. However in practical terms these patients are very difficult to define because there are no clinical tests of facet joint pain and there are a high propotion of positive results to placebo from prognostic blocks. Patients selected for facet denervation should firstly have a diagnostic block,twice with a very low volume of anaesthetic(0.5 ml) at the target location;they should have consistent results with at least 80% pain relief.( Dreyfuss 2000) There is a need for further high quality RCTs with larger patient samples. careful preselection of patients with diagnostic blocks, longer follow-ups and meaningful standardized outcomes.


References

1. Dreyfuss et al;Efficacy and validity of radiofrequency neurotomy for chronic lumbar zygoapohhysial joint pain. Spine,25(10):1270-7
2. Gallagher et al;Radiofrequency facet joint denervation in the treatment of low back pain: a prospective controlled double blind study to assess its efficacy.Pain Clin.7:193-198
3. Geurts et al;Efficacy of radiofrequency procedures for the treatment of spinal pain;a systematic review of randomized clinical trials. Reg.Anesth.Pain Med. 26(5):394-400
4. Lecraire et al:Radiofrequency facet joint denervation in the treatment of low back pain:a placebo-controlled clinical trial to assess efficacy.Spine: 26(13) 1411-6 discussion 7
5. Niemisto et al;Radiofrequency denervation for neck and back pain:a systematic review within the framework of the Cochrane collaboration back review group.Spine 28(16)1877-88
6. Van Kleef et al;Randomized trial of radiofrequency facet denervation for chronic low back pain. Spine 24(18)1937-42

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