The Internet Journal of Dermatology™ ISSN: 1531-3018

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Scrotal Leiomyoma

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Deba P. Sarma MD
Department of Pathology
Creighton University Medical Center

Eric E. Santos MD
Department of Pathology
St. Margaret's Hospital

Catherine E. Hagen BA
Department of Pathology
Creighton University Medical Center

Susan Repertinger MD
Department of Pathology
Creighton University Medical Center

Citation: D. P. Sarma, E. E. Santos, C. E. Hagen & S. Repertinger : Scrotal Leiomyoma . The Internet Journal of Dermatology. 2009 Volume 7 Number 1

Keywords: Leiomyoma of skin | smooth muscle tumor of skin | benign scrotal neoplasm

Case Report
Comment
Correspondence

Abstract

A rare case of scrotal leiomyoma occurring in a 47-year-old man is presented.

Case Report

This is a photomicrograph (Figure 1) of a biopsied painless, 6-mm scrotal nodule from a 47-year-old man that has been present for an unknown period of time. There was no history of trauma or previous surgical intervention. The epidermis is raised due to an eosinophilic dermal soft tissue tumor. The overlying epidermis is essentially normal. The dermal nodule is composed of bundles and fascicles of smooth muscle cells containing red fibrillar cytoplasm and elongated nuclei with blunted ends (Figure2). There is no cytologic atypia, increased or atypical mitosis, or necrosis.

Figure 1: Scrotal biopsy, low magnification.

Figure 2: Scrotal biopsy, high magnification

Comment

Leiomyoma of the scrotum, a benign smooth muscle tumor, may arise from the arrectores pilorum muscle (piloleiomyoma), vessel wall (angioleiomyoma), or most commonly from the dartos muscle of the scrotum (genital leiomyoma). Such tumors are quite rare. In 1976, Seigal and Gaffey reviewed the literature and their own cases and uncovered only 11 such cases among a total of 11,000 cases of scrotal tumor ¹. Occasional single cases have appeared in the literature since then ², ³. Scrotal leiomyoma is usually a single, painless, slow growing tumor occurring in middle-aged men. Simple excision is curative. Leiomyosarcoma, the malignant counterpart, is even rarer ⁴. Any cutaneous smooth muscle tumor showing rapid growth, large size, increased cellularity, cytologic atypia and 2 or more mitoses per 10 high power fields should be considered a leiomyosarcoma ⁵.

Correspondence

Deba P Sarma, MD
Department of Pathology
Creighton University Medical Center
Omaha, NE 68131
[debasarma@creighton.edu]

References

1. Siegal GP, Gaffey TA. Solitary leiomyomas arising from the tunica dartos scroti. J Urol. 116(1):69-71, 1976. (s)

2. Sherwani RK, Rahman K, Akhtar K, Zaheer S, Hassan MJ, Haider A. Leiomyoma of the scrotum. Indian J Pathol Microbiol. 51(1):72-3, 2008. (s)

3. Ohtake N, Maeda S, Kanzaki T, Shimoinaba K. Leiomyoma of the scrotum. Dermatology. 194(3), 1997. (s)

4. Moon TD, Sarma DP, Rodriguez FH Jr. Leiomyosarcoma of the scrotum. J Am Acad Dermatol. 20 (2 Pt 1), 1989. (s)

5. Raj S, Caljone E, Kraus M, Kavanagh G, Newman PL, Fletcher CD. Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol. 19:2-9, 1997. (s)

This article was last modified on Fri, 13 Feb 09 13:23:11 -0600

This page was generated on Sun, 21 Mar 10 23:57:48 -0500, and may be cached.


	The Internet Journal of Dermatology™ ISSN: 1531-3018 \| Home \| Editors \| Current Issue \| Archives \| Instructions for Authors \| Disclaimer \| Share with others \| Scrotal Leiomyoma Read printer friendly Subscribe in a reader Share with others Deba P. Sarma MD Department of Pathology Creighton University Medical Center Eric E. Santos MD Department of Pathology St. Margaret's Hospital Catherine E. Hagen BA Department of Pathology Creighton University Medical Center Susan Repertinger MD Department of Pathology Creighton University Medical Center Citation: D. P. Sarma, E. E. Santos, C. E. Hagen & S. Repertinger : Scrotal Leiomyoma . The Internet Journal of Dermatology. 2009 Volume 7 Number 1 Keywords: Leiomyoma of skin \| smooth muscle tumor of skin \| benign scrotal neoplasm Table of Contents Case Report Comment Correspondence Abstract A rare case of scrotal leiomyoma occurring in a 47-year-old man is presented. Case Report This is a photomicrograph (Figure 1) of a biopsied painless, 6-mm scrotal nodule from a 47-year-old man that has been present for an unknown period of time. There was no history of trauma or previous surgical intervention. The epidermis is raised due to an eosinophilic dermal soft tissue tumor. The overlying epidermis is essentially normal. The dermal nodule is composed of bundles and fascicles of smooth muscle cells containing red fibrillar cytoplasm and elongated nuclei with blunted ends (Figure2). There is no cytologic atypia, increased or atypical mitosis, or necrosis. Figure 1: Scrotal biopsy, low magnification. Figure 2: Scrotal biopsy, high magnification Comment Leiomyoma of the scrotum, a benign smooth muscle tumor, may arise from the arrectores pilorum muscle (piloleiomyoma), vessel wall (angioleiomyoma), or most commonly from the dartos muscle of the scrotum (genital leiomyoma). Such tumors are quite rare. In 1976, Seigal and Gaffey reviewed the literature and their own cases and uncovered only 11 such cases among a total of 11,000 cases of scrotal tumor ¹. Occasional single cases have appeared in the literature since then ², ³. Scrotal leiomyoma is usually a single, painless, slow growing tumor occurring in middle-aged men. Simple excision is curative. Leiomyosarcoma, the malignant counterpart, is even rarer ⁴. Any cutaneous smooth muscle tumor showing rapid growth, large size, increased cellularity, cytologic atypia and 2 or more mitoses per 10 high power fields should be considered a leiomyosarcoma ⁵. Correspondence Deba P Sarma, MD Department of Pathology Creighton University Medical Center Omaha, NE 68131 [debasarma@creighton.edu] References 1. Siegal GP, Gaffey TA. Solitary leiomyomas arising from the tunica dartos scroti. J Urol. 116(1):69-71, 1976. (s) 2. Sherwani RK, Rahman K, Akhtar K, Zaheer S, Hassan MJ, Haider A. Leiomyoma of the scrotum. Indian J Pathol Microbiol. 51(1):72-3, 2008. (s) 3. Ohtake N, Maeda S, Kanzaki T, Shimoinaba K. Leiomyoma of the scrotum. Dermatology. 194(3), 1997. (s) 4. Moon TD, Sarma DP, Rodriguez FH Jr. Leiomyosarcoma of the scrotum. J Am Acad Dermatol. 20 (2 Pt 1), 1989. (s) 5. Raj S, Caljone E, Kraus M, Kavanagh G, Newman PL, Fletcher CD. Cutaneous pilar leiomyoma: clinicopathologic analysis of 53 lesions in 45 patients. Am J Dermatopathol. 19:2-9, 1997. (s) This article was last modified on Fri, 13 Feb 09 13:23:11 -0600 This page was generated on Sun, 21 Mar 10 23:57:48 -0500, and may be cached.
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